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Michael B. Yaffe
Associate Professor
Biology
(MIT)
CONTACT
E18-850, 77 Massachusetts Avenue
Massachusetts Institute of Technology
Cambridge, MA 02139
Tel.: 617-452-2442
Email: myaffe@mit.edu
Web site: http://web.mit.edu/ki/faculty/yaffe.html
EDUCATION
Ph. D.: 1987, Case Western Reserve University
RESEARCH INTERESTS
Regulation of protein-protein interactions and signal transduction pathways by protein and lipid phosphorylation. Structure and function of modular signaling domains. Design of bioinformatics tools for proteomic analysis.
The goal of our research is to understand how protein phosphorylation controls progression through the cell cycle at the molecular level and how defects in phosphorylation bypass normal cell cycle checkpoints and lead to human cancer. We also study how protein and lipid phosphorylation controls the inflammatory response in phagocytic cells.
CURRENT TEAMS
This researcher is currently not associated with a team.
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