Photo of Kristala Prather

Kristala Prather

Arthur D. Little Professor

Chemical Engineering

MIT

+1 617-253-1950

Research Focus Areas

Research Interests

Metabolic engineering, synthetic biology, bioprocess/biochemical engineering. Design and assembly of novel pathways for the biological synthesis of small molecules. Protein engineering for pathway improvement. Bioprocess design and engineering for biopharmaceuticals, biofuels, and biochemicals.

Displaying 1 - 9 of 9

ICB Supported Publications

Carbon catabolite repression relaxation in Escherichia coli: global and sugar-specific methods for glucose and secondary sugar co-utilization

Kevin J Fox and Kristala LJ Prather

Current Opinion in Chemical Engineering, 2020

10.1016/j.coche.2020.05.005

Production of D‑Glyceric acid from d‑Galacturonate in Escherichia coli

Kevin J Fox, Kristala L J Prather

Journal of Industrial Microbiology & Biotechnology, 2020

10.1007/s10295-020-02323-2

Layered dynamic regulation for improving metabolic pathway productivity in Escherichia coli

Stephanie J. Doong, Apoorv Gupta, and Kristala L. J. Prather

PNAS, 2018

10.1073/pnas.1716920115

Scarless Cas9 Assisted Recombineering (no-SCAR) in Escherichia coli, an easy to use system for genome editing

Christopher Reisch, Kristala Prather

Current Protocols in Molecular Biology, 2018

10.1002/cpmb.29

Modular and selective biosynthesis of gasoline-range alkanes

Sheppard, M. J., Kunjapur, A. M. and Prather, K. L. J.

Metabolic Engineering, 2016

10.1016/j.ymben.2015.10.010

Screening and modular design for metabolic pathway optimization

Jason Boock, Apoorv Gupta, Kristala Prather

Current Opinion in Biotechnology, 2015

10.1016/j.copbio.2015.08.013

Retro-biosynthetic screening of a modular pathway design achieves selective route for microbial synthesis of 4-methyl-pentanol

M. J. Sheppard, A. M. Kunjapur, S. J. Wenck, and K. L. J. Prather

Nature Communications, 2014

10.1038/ncomms6031

Functional screening and in vitro analysis reveal thioesterases with enhanced substrate specificity profiles that improve short-chain fatty acid production in Escherichia coli

M. D. McMahon and K. L. J. Prather

Appl. Environ. Microbiol., 2014

10.1128/AEM.03303-13

Bioprospecting in the Genomic Age

Michael Hicks, Kristala Prather

Advances in Applied Microbiology, 2014

10.1016/B978-0-12-800261-2.00003-7