Michael Elowitz

Professor

Biology, Bioengineering & Applied Physics

Caltech

Caltech, 1200 E. California Blvd., MC 114-96

Identification of the fundamental design principles of regulatory and signaling gene circuits, and understanding how these circuits behave dynamically at the level of individual cells. Application of single-cell techniques and synthetic biology across a range of model systems from bacteria to mammalian cells.

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ICB Supported Publications

Morphogen gradient reconstitution reveals Hedgehog pathway design principles

Pulin Li, Joseph S. Markson, Sheng Wang, Siheng Chen, Vipul Vachharajani and Michael B. Elowitz

Science, 2018

10.1126/science.aao0645

Molecular time-sharing through dynamic pulsing in single cells

Jin Park, Marta Dies, Yihan Lin, Sahand Hormoz, Stephanie E. Smith-Unna, Sofia Quinodoz, Maria Jesus Hernandez-Jimenez, Jordi Garcia-Ojalvo, James C.W. Locke and Michael B. Elowitz

Cell Systems, 2018

10.1016/j.cels.2018.01.011

Combinatorial Signal Perception in the BMP Pathway

Yaron E. Antebi, James M. Linton, Heidi Klumpe, Bogdan Bintu, Mengsha Gong, Christina Su, Reed McCardell and Michael B. Elowitz

Cell, 2017

10.1016/j.cell.2017.08.015

An operational view of intercellular signaling pathways

Antebi, Y.E., Nandagopal, N. and Elowitz, M.B.

Current Opinion in Systems Biology, 2017

10.1016/j.coisb.2016.12.003