Stephen Mayo

Professor

Biology and Chemistry

Caltech

steve@mayo.caltech.edu

M/C 114-96, Broad Center

Developing and applying computational methods for the design and engineering of proteins with application areas ranging from biofuels to broad-spectrum antiviral therapeutics.

NAS 2004

Displaying 1 - 3 of 3

ICB Supported Publications

Functionalizing Hydrogel Nanovials with Vesicles Mimicking Antigen-Presenting Vesicles and Cancer Exosomes Improves T Cell Capture and Activation

Blade A. Olson, Michael Mellody, Citradewi Soemardy, Zhiyuan Mao, Anna Mei, Katie Lippert,
Magnus A. G. Hoffmann, Dino Di Carlo and Stephen L. Mayo

ACS NANO, 2026

https://doi.org/10.1021/acsnano.5c19139

Recruiting ESCRT to single-chain heterotrimer peptide MHCI releases antigen-presenting vesicles that stimulate T cells selectively

Blade A. Olson, Kathryn E. Huey-Tubman, Zhiyuan Mao, Magnus A. G.
Hoffmann, Pamela J. Bjorkman, Richard M. Murray, Stephen L. Mayo

PNAS, 2025

https://doi.org/10.1073/pnas.2501046122

Engineering transcriptional regulator effector specificity using computational design and in vitro rapid prototyping: Developing a vanillin sensor

de los Santos, E. L. C., Meyerowitz, J. T., Mayo, S. L. and Murray, R. M.

ACS Synthetic Biology, 2015

10.1021/acssynbio.5b00090