Stochastic simulation service: Bridging the gap between the compuational expert and the biologist

Abstract

We present StochSS: Stochastic Simulation as a Service, an integrated development environment for modeling and simulation of both deterministic and discrete stochastic biochemical systems in up to three dimensions. An easy to use graphical user interface enables researchers to quickly develop and simulate a biological model on a desktop or laptop, which can then be expanded to incorporate increasing levels of complexity. StochSS features state-of-the-art simulation engines. As the demand for computational power increases, StochSS can seamlessly scale computing resources in the cloud. In addition, StochSS can be deployed as a multi-user software environment where collaborators share computational resources and exchange models via a public model repository. We demonstrate the capabilities and ease of use of StochSS with an example of model development and simulation at increasing levels of complexity.

ICB Affiliated Authors

Authors
Drawert, B., Hellander, A., Bales, B., Banerjee, D., Bellesia, G., Daigle, Jr., B. J., Douglas, G., Gu, M., Gupta, A., Hellander, S., Horuk, C., Nath, D., Takkar, A., Wu, S., Lötstedt, P., Krintz, C. and Petzold, L. R.
Date
Type
Peer-Reviewed Article
Journal
PLoS Computational Biology
Volume
12
Pages
e1005220