Irene Chen

Assistant Professor

Chemistry & Biochemistry

UC Santa Barbara

chen@chem.ucsb.edu

Principles of molecular life and biochemical systems. Synthetic biology, molecular fitness landscapes, artificial life and origin of life, chemical biology.

News

Irene Chen Receives $2.1 Million NIH Director's New Innovator Award

ICB Project Leader Irene Chen Named a 2014 Searle Scholar

Displaying 1 - 8 of 8

ICB Supported Publications

Molecular Fitness Landscapes from High-Coverage Sequence Profiling

Celia Blanco, Evan Janzen, Abe Pressman, Ranajay Saha and Irene A. Chen

Annual Reviews of Biophysics, 2019

10.1146/annurev-biophys-052118-115333

Lipid vesicles chaperone an encapsulated RNA aptamer

Ranajay Saha, Samuel Verbanic and Irene A. Chen

Nature Communications, 2018

10.1038/s41467-018-04783-8

Analysis of in vitro evolution dynamics estimates ribozyme rates and the underlying distribution of activity among random sequences

Pressman, A., Moretti, J.E., Campbell, G.W., Muller, U.F. and Chen, I.A.

Nucleic Acids Research , 2017

10.1093/nar/gkx540

Quantitative analysis of synthesized nucleic acid pools

Xulvi-Brunet, R., Campbell, G.W., Rajamani, S., Jimenez, J. I. and Chen, I. A.

Nonlinear Dynamics in Biological Systems, 2016

10.1007/978-3-319-33054-9_2

Computational analysis of fitness landscapes and evolutionary networks from in vitro evolution experiments

Xulvi-Brunet, R., Campbell, G.W., Rajamani, S., Jimenez, J. I. and Chen, I. A.

Methods, 2016

dx.doi.org/10.1016/j.ymeth.2016.05.012

The RNA world as a model system to study the origin of life

Pressman, A., Blanco, C. and Chen, I. A.

Current Biology, 2015

10.1016/j.cub.2015.06.016

Molecular crowding and early evolution

R. Saha, A. Pohorille, and I. A. Chen

Origins of Life and Evolution of Biospheres, 2015

10.1007/s11084-014-9392-3

Experimental fitness landscapes to understand the molecular evolution of RNA-based life

S. S. Athavale, B. Spicer, and I. A Chen

Current Opinion in Chemical Biology, 2014

10.1016/j.cbpa.2014.09.008