Michael Mahan

Professor

Molecular, Cellular & Developmental Biology

UC Santa Barbara

+1 805-893-7160

michael.mahan@lifesci.ucsb.edu

Website

Research Focus Areas

Research Interests

The Mahan lab investigates the molecular mechanisms underlying microbial pathogenesis and the associated innate and adaptive immune responses that increase disease and compromise host immunity. The applied goal is to translate this research into effective therapeutic strategies for the treatment of multidrug-resistant pathogens and microbial sepsis.

News

ICB Researchers Develop Early Detection Test That Could Save Thousands of Lives

Collaborative Team Led by ICB Researchers Enables Simple, Rapid, Accurate, Inexpensive Covid-19 and Influenza Testing in the Palm of Your Hand

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ICB Supported Publications

Re-evaluation of FDA-approved antibiotics with increased diagnostic accuracy for assessment of antimicrobial resistance

Douglas M. Heithoff, Lucien Barnes V, Scott P. Mahan, Jeffrey C. Fried, Lynn N. Fitzgibbons, John K. House, Michael J. Mahan

Cell Reports Medicine, 2023

10.1016/j.xcrm.2023.101023

A Broad-spectrum Synthetic Antibiotic that does not Evoke Bacterial Resistance

Douglas M. Heithoff, Scott P. Mahan, Lucien Barnes V, Semen A. Leyn, Cyril X. George, Jaime E. Zlamal, Jakkarin Limwongyut, Guillermo C. Bazan, Jeffrey C. Fried, Lynn N. Fitzgibbons, John K. House, Charles E. Samuel, Andrei L. Osterman, David A. Low, and Michael J. Mahan

The Lancet, eBioMedicine, 2023

10.1016/j.ebiom.2023.104461

Coagulation factor protein abundance in the pre- septic state predicts coagulopathic activities that arise during late-stage murine sepsis

Douglas M. Heithoff, Genaro Pimienta, Scott P. Mahan, Won Ho Yang, Dzung T. Le, John K. House, Jamey D. Marth, Jeffrey W. Smith, and Michael J. Mahan

THE LANCET, eBioMedicine, 2022

10.1016/j.ebiom.2022.103965

Assessment of a Smartphone-Based Loop-Mediated Isothermal Amplification Assay for Detection of SARS-CoV-2 and Influenza Viruses

Douglas M. Heithoff, Lucien Barnes V, Scott P. Mahan, Gary N. Fox, Katherine E. Arn, Sarah J. Ettinger, Andrew M. Bishop, Lynn N. Fitzgibbons, Jeffrey C. Fried, David A. Low, Charles E. Samuel, Michael J. Mahan.

Jama Network Open, 2022

10.1001/jamanetworkopen.2021.45669