A schematic illustration of using DNA origami 2D array as template for epitaxial rearrangement of nanoparticles. The space group of DNA origami 2D array and the patterns of preorganized gold particles are highly programmable.
Nucleic acids provide unique building blocks to program nanoscale materials robustly and reproducibly using self-assembly into arbitrary 2D and 3D geometric patterns with nanometer-scale structural resolution.
Here, we propose to leverage our complementary DNA-based fabrication approaches for the rational design and synthesis of next-generation electromagnetic metamaterials. Specifically, we will explore fundamental principles of patterning inorganic nanostructures that can respond to a broad range of electromagnetic stimuli. We will develop approaches to build finite and extended 2D nanostructured DNA-based materials that template the assembly of inorganic nanostructures based on regular lattice spacings, and we will investigate methods to extend our ability to program complex materials with precise structures at the nanometer to millimeter length scales.
We will also investigate application of a bacterial expression platform we have developed to produce gram-quantities of sequence-specific single-stranded DNA scaffold for micron-to-millimeter-scale DNA-based materials production. Electromagnetic metamaterials have direct relevance to the needs of the ARO in the design of devices that have tailored optoelectronic properties, multiband electromagnetic adaptability, and facile integration into devices that provide advanced detection and protection of soldiers that are currently not realizable with conventional materials.