The Wilson Lab combines tools from Biology, Engineering, and Physics to understand the cell’s perceptual field. What can cells perceive? How do they perceive it? How do they make complex decisions? Ultimately we are interested in divining the design principles that enable complex signaling networks to process information. To this end we have become experts in combining light-switchable (optogenetic) molecules to precisely tune inputs to these molecular networks with a variety of fluorescent output reporters in our test-bed model system, human induced pluripotent stem cells.